Presenter: Dr. Sixiang Shi (MD Anderson Cancer Center, USA)
Topic: Nanomaterials for Molecular Imaging: an Emerging Paradigm
Time: 10：00 AM, Mar 12th (Monday)
Location: 910-308, Dushu Lake Campus
Abstract:
Molecular imaging has played an important role in cancer diagnosis. With the advances in nanotechnology, nanomaterials have emerged as a promising candidate for molecular imaging. In this presentation, tumor vascular targeting using different targeting ligands will be introduced for improving the targeting efficiency and specificity of nanoparticles. In addition, a novel chelator-free radiolabeling approach will be introduced for stable and efficient radiolabeling with several emerging nanomaterials. In the end, a biodegradable copper sulfide (CuS) nanosystem will be introduced for multispectral optoacoustic tomography (MSOT) in living animals. The degradation of CuS is controllable and temperature-dependent, making it a clinically-translatable in vivo theranostic platform with lower long-term side effects. Our studies provide a comprehensive and unique perspective for the designs and applications of novel nanomaterials, and may inspire future explorations into the realm of more controllable, multifunctional, and clinical relevant nanotheranostics.
Speaker Biography:
2016 - Present, Postdoctoral Fellow, MD Anderson Cancer Center, USA, (Professor Chun Li’s Group)
2011 - 2016, Ph.D., Materials Science Program, University of Wisconsin – Madison, USA, (Professor Weibo Cai’s group)
2007 - 2011, B.S., Materials Science and Engineering, Xi’an Jiaotong University, P.R. China
Research Interests
Molecular imaging, cancer therapy, design and characterization of nanomaterials.
Published papers >30; Conference presentations > 30
Contact: Dr. Liang Cheng
Editor: Juan Yang