Title: | Core–Shell MnSe@Bi2Se3 Fabricated via a Cation Exchange Method as Novel Nanotheranostics for Multimodal Imaging and Synergistic Thermoradiotherapy |
Authors: | Guosheng Song, Chao Liang, Hua Gong, Meifang Li, Xianchuang Zheng, Liang Cheng, Kai Yang,* Xiqun Jiang, and Zhuang Liu* |
Institutions: | Institute of Functional Nano and Soft Materials (FUNSOM) Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University School of Radiation Medicine and Protection and School for Radiological and Interdisciplinary Sciences (RAD-X), Medical College of Soochow University |
Abstract: | MnSe@Bi2Se3 core–shell nanostructures with highly integrated imaging and therapy functions are fabricated by a simple cation exchange method. Using those nanoparticles as a theranostic agent, a promise concept is further demonstrated to enhance conventional radiotherapy by: i) using X-ray absorbing agents to locally concentrate radiation energy and ii) employing near-infrared-light-triggered photothermal therapy to overcome hypoxia-associated radioresistance. |
IF: | 15.409 |
Link: | http://onlinelibrary.wiley.com/doi/10.1002/adma.201503006/abstract Editor: Danting Xiang |