Executive Director Prof. LIU, Zhuang

LIU, Zhuang

Tel: 0512-65882036 (O)   Email: zliu@suda.edu.cn, zliu828@gmail.com

Co-PI in the group: Cheng, Liang (Associate Professor)

Group webpage

Research Interests:

Nano-biotechnology, Novel Cancer Therapies, Drug Delivery, Biomedical Imaging, Nanotoxicology

Research Experience and Accomplishments:

Dr. Liu’s research in the past few years was mostly focused on the development of functional nanomaterials including carbon nanomaterials, upconversion nanoparticles, organic nanomaterials, protein-based carriers, and other multifunctional composite nanostructures, for the exploration of novel disease diagnostic and cancer therapeutic approaches. Starting from 2005, Dr. Liu has authored over 140 peer-reviewed papers, which have received a total citation of > 17,000 times and given him an H-index at 61. He was listed as one of the ‘Most Cited Chinese Researchers’ by Elsevier in 2014.

Academic Awards and Honors:

2015         NFSC Distinguished Young Scholar Award

2015         Fellow, Royal Society of Chemistry (FRSC)

2014         Young Chemist Award, Chinese Chemical Society, China

2013         Asian Rising Stars, 15th Asian Chemistry Congress, Singapore

2012         SCOPUS Young Researcher Award, China

2008         MRS Silver Award, Materials Research Society, USA

Editorial Activities:

Associate Editor, Biomaterials (2014-)

Editorial Board Member, Nano Research (2014-)

Editorial Board Member, Scientific Reports (NPG, 2013- )

Editorial Board Member, American Journal of Nuclear Medicine and Molecular Imaging (2012- )

Guest Editor, Nanoscale (2015)

Guest Editor, Carbon (2015)

Guest Editor, Advanced Healthcare Materials (2014)

Guest Editor, Theranostics (2012)

Position Opening:

We currently have 1-2 post-doc position openings for research directions in nanomedicine and nanobiotechnology. For those who are interested, please send your CV to Dr. Liu for consideration.

Publication /Citation List:

http://www.researcherid.com/rid/H-4352-2011

http://scholar.google.com/citations?hl=en&user=AIJbgl0AAAAJ

Selective Publications:

[36]Qian Chen, Xiaodong Liu, Jiawen Chen, Jianfeng Zeng*, Zhenping Cheng, Zhuang Liu* “A Self-assembled Albumin-based Nanoprobe for in vivo Ratiometric Photoacoustic pH Imaging” Adv. Mater. DOI: 10.1002/201503194 (in press)

[35]Guosheng Song, Chao Liang, Hua Gong, Meifang Li, Xianchuang Zheng, Liang Cheng, Kai Yang*, Xiqun Jiang, Zhuang Liu*, “Core-Shell MnSe@Bi2Se3 Fabricated via a Cation Exchange Method as Novel Nanotheranostics for Multimodal Imaging and Synergistic Thermo-radiotherapy” Adv. Mater. DOI: 10.1002/adma.201503000 (in press)

[34] Xuan Yi, Kai Yang*, Chao Liang, Xiaoyan Zhong, Ping Ning, Guosheng Song, Dongliang Wang, Cuicui Ge, Chunying Chen, Zhifang Chai and Zhuang Liu*, “Imaging-Guided Combined Photothermal and Radiotherapy to Treat Subcutaneous and Metastatic Tumors Using Iodine-131-Doped Copper Sulfide Nanoparticles” Adv. Funct. Mater. 25(29), 4689-4699(2015)

[33]Jian Xiang, Ligeng Xu*, Hua Gong, Wenwen Zhu, Chao Wang, Jun Xu, Liangzhu Feng, Liang Cheng, Rui Peng*, Zhuang Liu*,“Antigen-Loaded Upconversion Nanoparticles for Dendritic Cell Stimulation, Tracking, and Vaccination in Dendritic Cell-Based Immunotherapy” ACS Nano, 9, 6401-6411 (2015)

[32] Qian Chen, Xin Wang, Chao Wang, Liangzhu Feng, Yonggang Li, Zhuang Liu* “Drug-Induced Self-Assembly of Modified Albumins as Nano-theranostics for Tumor-Targeted Combination Therapy” ACS Nano, 9, 5223-5233 (2015)

[31] Xiaoqi Sun, Chao Wang, Min Gao, Aiyan Hu, Zhuang Liu* “Remotely controlled red blood cell carriers for cancer targeting and near-infrared light-triggered drug release in combined photothermal-chemotherapy”Adv. Funct. Mater. 25, 2386–2394 (2015)

[30]Teng Liu, Sixiang Shi, Chao Liang, Sida Shen, Liang Cheng, Chao Wang, Xuejiao Song, Shreya Goel, Todd E. Barnhart, Weibo Cai*, Zhuang Liu* “Iron Oxide Decorated MoS2 Nanosheets with Double PEGylation for Chelator-Free Radiolabeling and Multimodal Imaging Guided Photothermal Therapy” ACS Nano, 9, 950-960 (2015)

[29] Qian Chen, Chao Liang, Chao Wang, Zhuang Liu*, “An Imagable and Photothermal “Abraxane-Like” Nanodrug for Combination Cancer Therapy to Treat Subcutaneous and Metastatic Breast Tumors” Adv. Mater. 27, 903-910, (2015)

[28] Jingjing Liu, Chao Wang, Xiaojing Wang, Xin Wang, Liang Cheng, Yonggang Li, Zhuang Liu* “Mesoporous Silica Coated Single-Walled Carbon Nanotubes as a Multifunctional Light-Responsive Platform for Cancer Combination Therapy” Adv. Funct. Mater. 25, 384–392 (2015)

[27] Chao Wang, Ligeng Xu, Chao Liang, Jian Xiang, Rui Peng, Zhuang Liu* “Immunological responses triggered by photothermal therapy with carbon nanotubes in combination with anti-CTLA-4 therapy to inhibit cancer metastasis” Adv. Mater.26, 8154-8162 (2014)

[26] Liang Cheng, Chao Wang, Liangzhu Feng, Kai Yang, Zhuang Liu* “Functional Nanomaterials for Phototherapies of Cancer” Chem. Rev. 114(21), 10869-10939 (2014)

[25] Hua Gong, Ziliang Dong, Yumeng Liu, Shengnan Yin, Liang Cheng, Wenyao Xi, Jian Xiang, Kai Liu, Yonggang Li, Zhuang Liu* “Engineering of multifunctional nano-micelles for combined photothermal & photodynamic therapy under the guidance of multimodal imaging” Adv. Funct. Mater.24, 6492-6502 (2014)

[24] Chao Liang, Shuo Diao, Chao Wang, Hua Gong, Teng Liu, Guosong Hong, Xiaoze Shi, Hongjie Dai*, Zhuang Liu* “Tumor Metastasis Inhibition by Imaging-guided Photothermal Therapy with Single-walled Carbon Nanotubes” Adv. Mater. 26, 5646-5652 (2014)

[23] Chao Wang, Xiaoqi Sun, Liang Cheng, Shengnan Yin, Guangbao Yang, Yonggang Li, Zhuang Liu*, “Multifunctional theranostic red blood cells for magnetic field enhanced in vivo combination therapy of cancer” Adv. Mater. 26, 4794-4802 (2014)

[22] Liang Cheng, Wenjing Huang, Qiufang Gong, Changhai Liu, Zhuang Liu*, Yanguang Li* and Hongjie Dai “Ultra-Thin WS2 Nanoflakes as a Highly Efficient Electrocatalyst for Hydrogen Evolution Reaction” Angew. Chem. Int. Ed. 53, 7860-7863 (2014)

[21]Teng Liu, Chao Wang, Xing Gu, Hua Gong, Liang Cheng, Xiaoze Shi, Liangzhu Feng, Baoquan Sun, Zhuang Liu* "PEGylated MoS2 nano-sheets as a highly efficient versatile drug loading platform for combined chemo-&photothermal therapy of cancer" Adv. Mater. 26, 3433–3440 (2014)

[20]Liang Cheng, Jingjing Liu, Xing Gu, Hua Gong, Xiaoze Shi, Teng Liu, Chao Wang, Xiaoyong Wang, Gang Liu, Huaiyong Xing, Wenbo Bu, Baoquan Sun, Zhuang Liu* “PEGylated WS₂ nanosheets as a multifunctional theranostic agent for in vivo dual-modal CT / photoacoustic imaging guided photothermal therapy” Adv. Mater.26, 1886–1893, (2014)

[19] Zhiwei Li, Shengnan Yin, Liang Cheng, Kai Yang, Yonggang Li, Zhuang Liu* “Magnetic Targeting Enhanced Theranostic Strategy Based on Multimodal Imaging for Selective Ablation of Cancer” Adv. Funct. Mater. 24, 2312-2321 (2014)

[18] Xuejiao Song, Hua Gong, Shengnan Yin, Liang Cheng, Chao Wang, Zhiwei Li, Yonggang Li, Xiaoyong Wang, Gang Liu, Zhuang Liu* "Ultra-small Iron Oxide Doped Polypyrrole Nanoparticles for in vivo Multimodal Imaging Guided Photothermal Therapy" Adv. Funct. Mater. 24, 1194–1201 (2014)

[17] Hua Gong, Rui Peng*, Zhuang Liu* “Carbon nanotubes for biomedical imaging: The recent advances” Adv. Drug Delivery Rev.65, 1951–1963 (2013)

[16] Kai Yang, Liangzhu Feng, Hao Hong, Weibo Cai, Zhuang Liu*. “Preparation and functionalization of graphene nanocomposites for biomedical applications” Nature Protocols, 8, 2392-2403 (2013)

[15] Chao Wang, Huan Xu, Chao Liang, Yumeng Liu, Zhiwei Li, Guangbao Yang, Liang Cheng, Yonggang Li, Zhuang Liu* “Iron Oxide @ Polypyrrole Nanoparticles as a Multifunctional Drug Carrier for Remotely Controlled Cancer Therapy with Synergistic Antitumor Effect”ACS Nano, 7, 6782–6795 (2013)

[14] Chao Wang, Liang Cheng, Xinxing Ma, Xiaojing Wang, Yumeng Liu, Zhaoyi Deng, Yonggang Li, Zhuang Liu* “Imaging-guided pH Sensitive Photodynamic Therapy using Charge Reversible Upconversion Nanoparticles under Near-Infrared Light” Adv. Funct. Mater. 23, 3077-3086 (2013)

[13] Liang Cheng, Chao Wang, Xinxing Ma, Qinglong Wang, Yao Cheng, Han Wang, Yonggang Li, Zhuang Liu* “Multifunctional Upconversion Nanoparticles for Dual-modal Imaging Guided Stem Cell Therapy under Remote Magnetic Control” Adv. Funct. Mater. 23, 272-280 (2013)

[12] Kai Yang, Liangzhu Feng, Xiaoze Shi, Zhuang Liu* “Nano-graphene in biomedicine: theranostic applications” Chem. Soc. Rev. 42, 530-547 (2013)

[11] Liang Cheng, Chao Wang, Xinxing Ma, Qinglong Wang, Yao Cheng, Han Wang, Yonggang Li, Zhuang Liu* “Multifunctional Upconversion Nanoparticles for Dual-modal Imaging Guided Stem Cell Therapy under Remote Magnetic Control” Adv. Funct. Mater. 23, 272-280 (2013)

[10] Kai Yang, Huan Xu, Liang Cheng, Chunyang Sun, Jun Wang, Zhuang Liu* “In vitro and in vivo near-infrared photothermal therapy of cancer using polypyrrole organic nanoparticles”Adv. Mater.24, 5586-5592 (2012)

[9] Liang Cheng, Kai Yang, Qian Chen, Zhuang Liu*, “Organic Stealth Nanoparticles for Highly Effective in Vivo Near-Infrared Photothermal Therapy of Cancer” ACS Nano,6, 5605–5613 (2012) (Reported by C&E News)

[8] Xiaojing Wang, Chao Wang, Liang Cheng, Shuit-Tong Lee, Zhuang Liu* “Noble Metal Coated Single-walled Carbon Nanotubes for Applications in Surface Enhanced Raman Scattering Imaging and Photothermal Therapy” J. Am. Chem. Soc. 134, 7414–7422 (2012)

[7] Kai Yang, Lilei Hu, Xingxing Ma, Shuoqi Ye, Liang Cheng, Xiaoze Shi, Changhui Li, Yonggang Li, Zhuang Liu* “Multimodal imaging guided photothermal therapy using functionalized graphene nano-sheets anchored with magnetic nanoparticles” Adv. Mater. 24, 1868-1872 (2012) (Frontispieces Feature)

[6] Chao Wang, Xinxing Ma, Shouqi Ye, Liang Guo, Changhui Li, Yonggang Li*, Zhuang Liu* “Protamine functionalized single-walled carbon nanotubes for stem cell labeling and in vivo Raman / magnetic resonance / photoacoustic triple-modal imaging” Adv. Funct. Mater. 22, 2363–2375 (2012)

[5] Bo Tian, Chao Wang, Shuai Zhang, Liangzhu Feng, Zhuang Liu* “Photothermally Enhanced Photodynamic Therapy Delivered by Nano-Graphene Oxide” ACS Nano, 5, 7000-7009 (2011)

[4] Liang Cheng, Kai Yang, Yonggang Li, Jianhua Chen, Chao Wang, Mingwang Shao*, Shuit-Tong Lee, Zhuang Liu* “Facile preparation of multifunctional upconversion nanoprobes for multi-modal imaging and dual-targeted photothermal therapy” Angew. Chem. Int. Ed. 50, 7385-7390 (2011)

[3] Kai Yang, Jianmei Wan, Shuai Zhang, Youjiu Zhang, Shuit-Tong Lee, Zhuang Liu* “In vivo Pharmacokinetics, Long-Term Biodistribution, and Toxicology of PEGylated Graphene in Mice” ACS Nano, 5, 516-522 (2011)

[2] Chao Wang, Liang Cheng, Zhuang Liu,* “Drug Delivery with Upconversion Nanoparticles for Multi-Functional Targeted Cancer Cell Imaging and Therapy” Biomaterials,32, 1110-1120 (2011)

[1] Kai Yang, Shuai Zhang, Guoxin Zhang, Xiaoming Sun, Shuit-Tong Lee and Zhuang Liu,* “Graphene in Mice – Ultra-high in vivo Tumor Uptake and Highly Efficient Photothermal Therapy” Nano Lett. 10, 3318–3323 (2010)(Highlighted by Nature)

Contact: 0512-65882036

E-mail: zliu@suda.edu.cn

Edited by Juan Yang