WANG, Chao

time:2017-07-11Hits:2130设置

Name

Chao WANG Ph.D.

  

Title

Professor

  

Academic history:

B.S., Soochow University, School of Life Sciences, 2010;

Ph.D., Soochow University, Institute of Functional Nano & Soft Materials (FUNSOM), 2014;

Postdoctoral Researcher, University of North Carolina at Chapel Hill & North Carolina State University, Dept. of Joint Department of Biomedical Engineering; 2015-2018

  

Research interests:

Immunoengineering;

Cell-based Biomaterials;

Cancer immunotherapy;

Drug delivery

  

Research accomplishments:

Our lab current research focuses include development of cell-based biomaterials for immunoengineering, tissue engineering and regeneration, in order to develop effective novel immunotherapies for cancer, infectious diseases, autoimmune disorders and age-related disease. Dr. Wang has authored over 70 peer-reviewed papers, which have received a total citation of > 5,500 times and given him an H-index at 41 (Google Scholar). Dr. Wang has been selected as a TR35 by the Asia-Pacific MIT Technology Review and has been included in Clarivate's Highly Cited Scientists for five consecutive years.


  

Selected publications:

[18] Qianyu Yang, Huaxing Dai, Beilei Wang, Jialu Xu, Yue Zhang, Yitong Chen, Qingle Ma, Fang Xu, Haibo Chen, Dongdong Sun*, Chao Wang*. Nanoplastics Shape Adaptive Anticancer Immunity in the Colon in Mice. Nano Letters, (2023).

[17] Qianyu Yang#, Huaxing Dai#, Ying Cheng#, Beilei Wang, Jialu Xu, Yue Zhang, Yitong Chen, Fang Xu, Qingle Ma, Fang Lin* and Chao Wang*. Oral Feeding of Nanoplastics affects Brain function of Mice by Inducing Macrophage IL-1 signal in Intestine. Cell Reports, 42, 112346 (2023).

[16] Yitong Chen, Yue Zhang, Beilei Wang, Qin Fan, Qianyu Yang, Jialu Xu, Huaxing Dai, Fang Xu, Chao Wang*. Blood Clot Scaffold Load with Liposome Vaccine and siRNAs Targeting PD-L1 and TIM-3 for Effective DC Activation and Cancer Immunotherapy. ACS Nano, 17, 760 (2023). Link

[15] Fang Xu*, Yi Wu, Qianyu Yang, Ying Cheng, Jialu Xu, Yue Zhang, Huaxing Dai, Beilei Wang, Qingle Ma, Yitong Chen, Fang Lin, Chao Wang*. Engineered extracellular vesicles with SHP2 high expression promote mitophagy for Alzheimer’s disease treatment. Advanced Materials, 2207107, (2022). Link

[14] Beilei Wang, Jinyu Bai*, Bo Tian, Hao Chen, Qianyu Yang, Yitong Chen, Jialu Xu, Yue Zhang, Huaxin Dai, Qingle Ma, Ziyin Fei, Heng Wang, Fang Xu, Xiaozhong Zhou*, Chao Wang*. Genetically Engineered Hematopoietic Stem Cells Deliver TGF-β Inhibitor to Enhance Bone Metastases Immunotherapy. Advanced Science, 2201451 (2022). Link

[13] Jialu Xu, Qingle Ma, Yue Zhang, Ziying Fei, Yifei Sun, Qin Fan, Bo Liu, Jinyu Bai, Yue Yu, Jianhong Chu*, Jingrun Chen*, Chao Wang*. Yeast-derived nanoparticles remodel the immunosuppressive microenvironment in tumor and tumor-draining lymph nodes to suppress tumor growth. Nature Communications, 13, 110 (2022). Link

[12] Huaxing Dai, Qin Fan, Ziying Fei, Qingle Ma, Qianyu Yang, Jiacheng Chu, Xuanfang Zhou, Yue Zhang, Ziliang Dong, Fang Xu, Beilei Wang, Rong Sun, Yifan Shen, Ruao Xie, Ruibin Li and Chao Wang*. Systemically Administered Silica Nanoparticles Result in Diminished T cell Response in Lung. Nano Today 42, 101332 (2022). Link

[11] Qin Fan#, Huaxing Dai#, Jinyu Bai#, Jialu Xu, Qingle Ma, Ziying Fei, Xiaozhong Zhou*, Kam W. Leong*, Chao Wang*. Degradation-resistant Implanted Biomaterials Establish an Immunosuppressive Microenvironment that Induces T Cell Exhaustion by Recruiting Myeloid Cells. Fundamental Research (2022). Link

[10] Fang Xu, Ziying Fei, Huaxing Dai, Jialu Xu, Qin Fan, Shufang Shen, Yue Zhang, Qingle Ma, Jiacheng Chu, Fei Peng, Fangfang Zhou, Zhuang Liu, Chao Wang*. Mesenchymal Stem Cell-derived Extracellular Vesicles with High PD-L1 Expression for Autoimmune Diseases Treatment. Advanced Materials, 34, 2106265 (2022). Link

[9] Yue Zhang, Jialu Xu, Ziying Fei, Huaxing Dai, Qin Fan, Qianyu Yang, Yitong Chen, Beilei Wang, Chao Wang*. 3D Printing Scaffold Vaccine for Antitumor Immunity. Advanced Materials, 33, 2106768 (2021). Link

[8] Shufang Shen, Huaxing Dai, Ziying Fei, Yu Chai, Yu Hao, Qin Fan, Ziliang Dong, Yujie Zhu, Jialu Xu, Qingle Ma, Xiao Han, Ligeng Xu, Fei Peng, Zhuang Liu, Chao Wang*. Immunosuppressive Nanoparticles for Management of Immune-Related Adverse Events in Liver. ACS Nano, 5, 9111 (2021). Link

[7] Qin Fan, Jinyu Bai, Huajian Shan, Ziying Fei, Hao Chen, Jialu Xu, Qingle Ma, Xiaozhong Zhou* and Chao Wang*. Implantable Blood Clot Loaded with BMP-2 for Regulation of Osteoimmunology and Enhancement of Bone Repair. Bioactive Materials, 6, 4014 (2021). Link

[6] Ziying Fei, Qin Fan*, Huaxing Dai, Xuanfang Zhou, Jialu Xu, Qingle Ma, Atsushi Maruyama*, Chao Wang*. Physiologically Triggered Injectable Red Blood Cell-Based Gel for Tumor Photoablation and Enhanced Cancer Immunotherapy. Biomaterials, 271, 120724 (2021)Link

[5] Qin Fan, Qingle Ma, Jinyu Bai, Jialu Xu, Ziying Fei, Ziliang Dong, Atsushi Maruyama, Kam W. Leong, Zhuang Liu and Chao Wang*. An Implantable Blood Clot-based Immune Niche for Enhanced Cancer Vaccination. Science Advances, 6, eabb4639 (2020). Link [Biotechscope]

[4] Qingle Ma, Qin Fan, Jialu Xu, Jinyu Bai, Xiao Han, Ziliang Dong, Xiaozhong Zhou, Zhuang Liu, Zhen Gu* and Chao Wang*. Calming Cytokine Storm in Pneumonia by Targeted Delivery of TPCA-1 Using Platelet-derived Extracellular Vesicles. Matter, 3, 287 (2020). Link [Matter]

[3] Xuanfang Zhou, Zhouqi Meng*, Jialin She, Yaojia Zhang, Xuan Yi, Hailin Zhou, Jing Zhong, Ziliang Dong, Xiao Han, Muchao Chen, Qin Fan, Kai Yang and Chao Wang* . Near-Infrared Light-Responsive Nitric Oxide Delivery Platform for Enhanced Radioimmunotherapy. Nano-Micro Letters, 12, 100 (2020).

[2] Lin Zhang, Jinhua Zhou, Lvzhong Hu, Xiao Han, Xinwei Zou, Qian Chen, Youguo Chen*, Zhuang Liu*, Chao Wang*. In Situ Formed Fibrin Scaffold with Cyclophosphamide to Synergize with Immune Checkpoint Blockade for Inhibition of Cancer Recurrence after Surgery. Advanced Functional Materials, 1906922 (2019). 

[1] Xiao Han#, Shufang Shen#, Qin Fan, Guojun Chen, Edikan Archibong, Gianpietro Dotti, Zhuang Liu*, Zhen Gu* and Chao Wang*. Red Blood Cell Derived Nanoerythrosome for Antigen Delivery with Enhanced Cancer ImmunotherapyScience Advances, 5, eaaw6870 (2019).

 

Full publication list can be found at

 

https://scholar.google.com/citations?user=t3ljbdoAAAAJ&hl

http://www.researcherid.com/rid/G-5951-2012


  

Contact information:cwang@suda.edu.cn, wangch2010@gmail.com



Edited by Juan Yang

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